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Nitrates, alpha-blockers, antihypertensives or alcohol – tadalafil can potentiate the hypotensive effects; CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) – increase tadalafil exposure requiring dose adjustment. Tadalafil for use as needed: no more than 10 mg every 72 hours. For once daily use: dose not to Cialis 2.5mg, 5mg, 10mg & 20mg film-coated tablets – -…Thus, in a patient prescribed any dose of CIALIS (2.5 mg- 20 mg), where nitrate administration is deemed medically necessary in a life-threatening situation, at least 48 hours should have elapsed after the last dose of CIALIS before nitrate administration is considered. In such circumstances, nitrates should only be Amazon.com: Rev72 -Powerful 72 Hour All Natural Peak…REV72 will deliver peak performance over 72 hours and is the strongest product on the market today!. Why settle for a product that over promises, under delivers and uses a cartoon to advertise. 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